DBM - Demineralized Bone Matrix Cubes

DBM Cubes are structural allograft blocks created from demineralized human cortical bone. This unique supercritical CO₂ processing ensures deep cleaning, virus inactivation (SAL 10⁻⁶), and preservation of the bone morphogenetic proteins (BMPs) responsible for osteoinduction.

The cube format provides both volume stability and biological performance, making it suitable for reconstructive procedures requiring a balance between mechanical support and rapid biological integration. Their natural porosity allows for vascular ingrowth and osteogenesis, while the demineralized surface promotes cell differentiation and bone regeneration.

Composition: 100% demineralized cortical bone in cube form.

Structure: Porous, resorbable scaffold with preserved osteoinductive growth factors.

Biological Properties:

• Osteoconductive: Provides a scaffold for bone ingrowth.

• Osteoinductive: Stimulates differentiation of progenitor cells into osteoblasts.

• Biocompatible: Integrates seamlessly with host bone and remodels naturally.

Indications for Use

• Orthopedic & Trauma Surgery: Filling segmental defects, fracture reconstruction, revision cases.

• Spinal Surgery: Used in cervical and lumbar fusion procedures where structural support is required.

• Dental & Maxillofacial Surgery: Sinus lifts, ridge augmentations, and cavity fillings.

• Oncology & Tumor Resection: Reconstruction of bone defects post-excision.

Available Sizes:

• Standard cube sizes: 5 mm, 10 mm, 15 mm, and 20 mm (custom sizes available upon request).